Waiver Wire Targets for Week 16 (2025 Fantasy Football) 

Waiver Wire Strategy for Week 16 

I will be publishing one more waiver wire column next week (week 17).  Week 18 is always a bit of a crapshoot based on playoff teams resting starters, etc.   

Top 5 Waiver Wire Targets – Week 16 

Here are my Top fantasy football waiver wire pickups for Week 16

  1. RB, Jacory Croskey-Merritt 
  1. WR, Jayden Reed 
  1. RB, Jawhar Jordan (pending status of Chubbs and Woods) 
  1. QB, Marcus Mariota 
  1. TE, Colby Parkinson 

Waiver Wire Pickups by Position 

Quarterbacks 

  • Marcus Mariota 
  • Sam Darnold 
  • Tyler Shough 
  • Bryce Young 
  • Trevor Lawrence 

Running Backs 

  • Jacory Croskey-Merritt 
  • Jawhar Jordan 
  • Audric Estime 
  • Keaton Mitchell 

Wide Receivers 

  • Jayden Reed 
  • Adonai Mitchell 
  • Luther Burden III 
  • Devaughn Vele 
  • Darius Slayton 
  • Kayshon Boutte 

Tight Ends 

  • Colby Parkinson 
  • Dalton Schultz 
  • Colston Loveland 
  • Brenton Strange 
  • Theo Johnson 

Defenses (DST) 

  • Buffalo (vs CLE) 
  • Minnesota (vs NYG) 
  • Atlanta (vs Ari) 

Published by Sean Ryan

About Sean Ryan — Founder of the Fantasy Football Almanac & Functional Sportsaholic Sean has been passionate about football and sports analysis since his early days writing for NFL Draft Blitz from 1999 to 2005 — back when the term “blog” wasn’t even popular. After building a successful career in business development and marketing, Sean returned to his true passion in 2016 by creating Functional Sportsaholic, home to the Fantasy Football Almanac and Draft Guide and a premier sports betting service. A lifelong fan of Baltimore/DC sports, Sean grew up following the Orioles and Redskins before shifting his focus to the NFL after pivotal moments shaped his fandom. Today, Sean calls himself an avid NFL fan and fantasy football expert who combines deep NFL film study with data-driven analytics to deliver unique insights. Sean’s expertise lies in analyzing NFL coaching strategies and player usage — the “Xs and Os” — to help fantasy football players dominate their drafts and win their leagues. When he’s not breaking down film or crunching numbers, Sean enjoys connecting with the fantasy sports community and helping new voices emerge through podcasts, videos, and written content.

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